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Clinical versus pathologic diagnosis: acrodermatitis enteropathica.

Alicia Fernandez Sein1

  • 1Section of Pediatric Critical Care, Department of Pediatrics, UPR School of Medicine, San Juan, PR 00936-5067. alicia.fernandez@upr.edu

Boletin De La Asociacion Medica De Puerto Rico
|September 22, 2010
PubMed
Summary
This summary is machine-generated.

Malnutrition causes infant illness and death. Visual diagnosis of skin issues from zinc deficiency, like Acrodermatitis Enteropathica, is confirmed by patient history and response to treatment.

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Area of Science:

  • Pediatrics
  • Dermatology
  • Nutritional Science

Background:

  • Malnutrition remains a significant cause of infant morbidity and mortality, even in developed nations.
  • It affects all organ systems, with skin manifestations being particularly common and often diagnosed visually.
  • Chronic and critical illnesses can lead to malnutrition due to insufficient dietary intake.

Observation:

  • Four cases of malnutrition with associated zinc deficiency are presented.
  • The clinical diagnosis of these cases was accurate.
  • Skin manifestations in these patients were the primary diagnostic indicators.

Findings:

  • Acrodermatitis Enteropathica, a condition resulting from zinc deficiency, shares histological similarities with other deficiency dermatoses and psoriasis.
  • Clinical diagnosis of zinc deficiency dermatitis is achievable through careful patient history and physical examination.
  • Therapeutic response to zinc supplementation is a key factor in confirming the diagnosis.

Implications:

  • Visual diagnosis of skin manifestations in malnutrition, particularly zinc deficiency, is reliable.
  • A detailed patient history and physical exam are crucial for diagnosing Acrodermatitis Enteropathica.
  • Effective treatment relies on recognizing clinical signs and confirming with therapeutic outcomes.