Multiple schwannomatosis caused by the recently described INI1 gene--molecular pathology, and implications for
Paul M Brennan1, Antonio Barlow, Alistair Geraghty
1Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK. paul.brennan@ed.ac.uk
British Journal of Neurosurgery
|September 22, 2010
Abstract:
The most common genetic predisposition to multiple schwannoma growth is mutation of the neurofibromatosis type 2 gene. We describe a patient with multiple schwannomas and mutation in the recently described INI1 gene, which also predisposes to the disease. We explore the implications for prognosis and outcome.
