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Related Experiment Video

Updated: Jun 8, 2026

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing

Published on: December 1, 2023

A unique presentation of epignathus.

Janna Joethy¹, Yong Chen Por, Yeow Vincent

¹Singapore General Hospital, Singapore. janajoethy@hotmail.com

The Journal of Craniofacial Surgery

|September 22, 2010

Summary

Epignathus, a rare nasopharyngeal tumor, can cause palatal clefts and respiratory issues. Early diagnosis and multidisciplinary management are crucial for affected infants.

Area of Science:

Oral and Maxillofacial Surgery
Developmental Biology
Pediatric Oncology

Background:

Palatal clefts can be associated with space-occupying lesions in the oral or nasal cavities.
These lesions may offer insights into the developmental origins of palatal clefts.
Epignathus is a rare congenital tumor with potential to cause significant morbidity.

Observation:

Epignathus, a nasopharyngeal tumor, originates from the upper jaw, palate, or sphenoid bone.
Tumors can protrude through the oral cavity, leading to respiratory distress.
The exact pathogenesis of epignathus remains unclear, with multiple theories proposed.

Findings:

Epignathus presents as a rare space-occupying tumor.
Clinical presentation includes potential respiratory compromise and airway obstruction.

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Management strategies are contingent upon tumor size and patient condition.

Implications:

Understanding epignathus contributes to the etiology of certain palatal clefts.
Multidisciplinary care is essential for optimal patient outcomes.
Further research into epignathus pathogenesis may reveal novel therapeutic targets.