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Updated: Jun 8, 2026

Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods
Published on: March 10, 2020
Ventricular noncompaction and associated cardiac anomalies
Mikhailia Lake1, Stamatios Lerakis, Jacob Green
1Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland 21205, USA. mlake3@jhmi.edu
Abstract:
An 80-year-old woman was referred for transcatheter aortic valve implantation for correction of aortic stenosis. An echocardiogram at the author's institution revealed severe hypertrophy of the left ventricle with deep recesses into the myocardium and hypokinesis involving the left ventricular apex. In addition, there was subaortic stenosis secondary to a muscular ridge. The aortic valve was only mildly stenotic. In this Cardiology Grand Rounds, the authors present a rare case of ventricular noncompaction and review the literature on this subject and its association with other cardiac abnormalities.
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