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Updated: Feb 10, 2026

Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line
Published on: September 28, 2022
A case of unilateral optic disc swelling with chronic active Epstein-Barr virus infection
Naoko Aizawa1, Toru Nakazawa, Masahiko Shimura
1Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan. n.aizawa@oph.med.tohoku.ac.jp
Abstract:
Ocular complications of chronic active Epstein-Barr virus (EBV) infection have rarely been reported and are usually associated with systemic symptoms. We described a 17-year-old boy with unilateral optic disc swelling without any systemic symptoms at the initial onset. Antibody titers to EBV were markedly elevated. Treatment with immunosuppressants and corticosteroids dramatically relieved all his symptoms, including unilateral optic swelling and visual field abnormalities.
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