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Effect of dexamethasone on IL-1 and IL-3-LA release by unstimulated human mononuclear cells

R Djaldetti1, P Fishman, V Shtatlender

  • 1Department of Medicine B, Golda Medical Center, Hasharon Hospital, Petah Tikva, Israel.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|January 1, 1990
PubMed

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...