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Bimetallic reductive elimination from dinuclear Pd(III) complexes.

David C Powers1, Diego Benitez, Ekaterina Tkatchouk

  • 1Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.

Journal of the American Chemical Society
|September 23, 2010
PubMed
Summary
This summary is machine-generated.

This study investigates reductive elimination from dinuclear palladium(III) complexes, revealing that the intact dinuclear core and redox synergy between metals drive facile C-halogen bond formation.

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Area of Science:

  • Organometallic Chemistry
  • Catalysis
  • Reaction Mechanisms

Background:

  • Previous work reported C-halogen reductive elimination from dinuclear Pd(III) complexes in 2009.
  • Dinuclear intermediates were implicated in Pd(OAc)2-catalyzed C-H oxidation.

Purpose of the Study:

  • To thoroughly investigate the mechanism of reductive elimination from dinuclear Pd(III) complexes.
  • To establish the specific role of each palladium metal center during reductive elimination.

Main Methods:

  • Experimental investigation of dinuclear Pd(III) complexes.
  • Theoretical computational studies to elucidate reaction pathways.

Main Results:

  • Reductive elimination occurs from a complex where the dinuclear palladium core remains intact.
  • Evidence suggests that redox synergy between the two palladium metals facilitates the reaction.
  • The mechanism clarifies the distinct roles of each metal in the reductive elimination process.

Conclusions:

  • Dinuclear Pd(III) complexes facilitate C-halogen reductive elimination through an intact core mechanism.
  • Redox synergy between palladium centers is crucial for the observed facile reductive elimination.
  • This understanding provides key insights into palladium-catalyzed oxidation reactions.