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Systolic thickening increases from subepicardium to subendocardium
J A Gascho1, G L Copenhaver, D F Heitjan
1Division of Cardiology, Milton S Hershey Medical Center, Pennsylvania State University, Hershey 17033.
Study Objective:
The aim was to determine the relation between systolic function and depth below the epicardial surface, using pulsed Doppler crystals.
Design:
Systolic excursion in mm was measured at multiple depths below the epicardial surface. Measurements were made during control conditions.
Subjects:
Thirty four anaesthetised mongrel dogs were studied.
Measurements And Main Results:
A total of 333 measurements of systolic excursion were made during control conditions at 1 to 3 crystal sites per dog. Two models were constructed; the model which assumed a quadratic relation between depth (d) and systolic excursion (EX) (EX = 0.498 + 0.176d + 0.006d2) fit the data better than did a model which assumed a linear relation (EX = -0.0716 + 0.254d).
Conclusions:
These data support the prediction from geometric models that systolic excursion increases in a non-linear fashion from subepicardium to subendocardium.