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Published on: May 16, 2025
Abatacept therapy for rheumatoid arthritis in the setting of hepatitis C infection
Tina Dewan Mahajan1, Roderick Hooker, Lisa Maher
1Dallas VA Medical Center and University of Texas Southwestern Medical Center, Dallas, TX, USA.
Abstract:
Chronic hepatitis C in the setting of rheumatoid arthritis may be an obstacle to optimal management because of potential hepatotoxicity and adverse effects from immune suppression in these patients with a chronic infection. There are no reports in the literature discussing the use of abatacept, a T-cell costimulatory blocker, in patients with chronic hepatitis C. This article is the first report to describe the use of abatacept in 2 patients with rheumatoid arthritis and concomitant hepatitis C with favorable outcome.
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