Pre-donation deferral of blood donors in South Indian set-up: An analysis

P Sundar1, S K Sangeetha, D M Seema

  • 1Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore - 560 029, India.

Insights

Blood donation deferral rates are higher in females due to low hemoglobin, low body weight, and hypotension. Younger donors also show higher deferral rates, primarily for low hemoglobin.

Area of Science:

  • Transfusion Medicine
  • Hematology
  • Public Health

Background:

  • Many healthy individuals are deferred from blood donation for various reasons.
  • Understanding deferral patterns is crucial for maintaining blood supply safety and adequacy.

Purpose of the Study:

  • To analyze the rate and causes of blood donor deferrals.
  • To identify demographic factors influencing deferral rates in a Bangalore Transfusion Medicine Centre.

Main Methods:

  • Retrospective analysis of donor records from January 2005 to December 2007.
  • Data categorized by age groups, sex, and deferral reasons.
  • Comparison of deferral rates between males and females.

Main Results:

  • Overall deferral rate was 5.84% (976 out of 16,706 donors).
  • Females had a significantly higher deferral rate (19.85%) compared to males (4.06%).
  • Common deferral reasons: low hemoglobin, low body weight, hypotension (females); hypertension, underweight, low hemoglobin (males).
  • Highest deferral rates observed in the 18-25 age group, predominantly due to low hemoglobin.

Conclusions:

  • Female blood donors are deferred at a much higher rate than males.
  • Low hemoglobin levels are a primary cause for deferral across various demographics.
  • Targeted interventions may improve donor retention and blood supply.
Abstract

Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Rh Blood Group01:19

Rh Blood Group

The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.