Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of a new suturing technique for tendon graft preparation: an animal cadaver study.

Clinical biomechanics (Bristol, Avon)·2015
Same author

Dynamic in vitro analysis of tractile forces of the anterior cruciate ligament (ACL) transplant using patellar and semitendinosus muscle tendon: a cadaver study.

Archives of orthopaedic and trauma surgery·2014
Same author

[Damage to implants due to high-frequency electrocautery : analysis of four fractured hip endoprostheses shafts].

Der Orthopade·2014
Same author

Tissue attachment strength and adhesion formation of intraabdominal fixed meshes with cyanoacrylat glues.

European journal of medical research·2008
Same author

Operative treatment of greater tuberosity fractures of the humerus--a biomechanical analysis.

Clinical biomechanics (Bristol, Avon)·2007
Same author

[Photoelastic stress analysis of human femurs before and after implantation of different models of femur neck prostheses].

Zeitschrift fur Orthopadie und ihre Grenzgebiete·2007
Same journal

[Fast-track hip and knee joint arthroplasty].

Der Orthopade·2022
Same journal

[Outpatient care through cross-sector prehabilitation and rehabilitation concepts in outpatient hip and knee arthroplasty].

Der Orthopade·2022
Same journal

[Preoperative management in fast-track arthroplasty].

Der Orthopade·2022
Same journal

[Perioperative management in fast-track arthroplasty].

Der Orthopade·2022
Same journal

[Pain therapy and anaesthesiological procedures in fast-track arthroplasty].

Der Orthopade·2022
Same journal

[Discharge readiness versus discharge-Results of the PROMISE study].

Der Orthopade·2022
See all related articles

Related Experiment Video

Updated: Jun 8, 2026

A Flexible Wearable Supernumerary Robotic Limb for Chronic Stroke Patients
03:55

A Flexible Wearable Supernumerary Robotic Limb for Chronic Stroke Patients

Published on: October 27, 2023

[Material and technical aspects of mega prostheses].

W Plitz1

  • 1bwolfgang.plitz@t-online.de

Der Orthopade
|September 23, 2010
PubMed
Summary
This summary is machine-generated.

Mega implants, custom-made for tumor therapy, bypass standard medical device testing. Manufacturing relies on casting cobalt-chromium-molybdenum alloys and CT scans for precise patient customization.

More Related Videos

Engineering Platform and Experimental Protocol for Design and Evaluation of a Neurally-controlled Powered Transfemoral Prosthesis
11:16

Engineering Platform and Experimental Protocol for Design and Evaluation of a Neurally-controlled Powered Transfemoral Prosthesis

Published on: July 22, 2014

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study
06:58

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study

Published on: November 6, 2015

Related Experiment Videos

Last Updated: Jun 8, 2026

A Flexible Wearable Supernumerary Robotic Limb for Chronic Stroke Patients
03:55

A Flexible Wearable Supernumerary Robotic Limb for Chronic Stroke Patients

Published on: October 27, 2023

Engineering Platform and Experimental Protocol for Design and Evaluation of a Neurally-controlled Powered Transfemoral Prosthesis
11:16

Engineering Platform and Experimental Protocol for Design and Evaluation of a Neurally-controlled Powered Transfemoral Prosthesis

Published on: July 22, 2014

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study
06:58

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study

Published on: November 6, 2015

Area of Science:

  • Biomaterials Engineering
  • Orthopedic Surgery
  • Medical Device Manufacturing

Context:

  • Mega implants are custom-designed prostheses for treating extensive bone tumor diseases.
  • Standard testing protocols under the German Act on Medical Devices do not apply to these custom-made devices.
  • Unique manufacturing constraints necessitate specialized techniques for mega implant production.

Purpose:

  • To outline the specific manufacturing processes and material considerations for mega implants used in tumor therapy.
  • To address the exclusion of custom-made mega prostheses from conventional medical device testing.
  • To highlight the role of advanced technologies in customizing these implants for individual patients.

Summary:

  • Mega implants, developed for tumor treatment, are custom-made and thus exempt from standard medical device testing.
  • Casting technologies are exclusively used for these prostheses, primarily employing Cobalt-Chromium-Molybdenum (Co-Cr-Mo) cast alloys.
  • Computerized Tomography (CT) scans create plastic models for precise customization, with surface modifications enhancing osseointegration.

Impact:

  • Ensures appropriate manufacturing methods for complex, patient-specific orthopedic implants.
  • Facilitates the development and application of specialized implants for challenging oncological cases.
  • Advances the customization and integration of prosthetic devices in reconstructive surgery.