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[Relation between oxygen consumption and oxygen delivery in chronic obstructive pulmonary diseases and chronic cor
1Respiratory Disease Research Center, Red-Cross Chao-yang Hospital, Beijing.
Abstract:
An investigation of 13 cases of COPD and 15 cases of chronic cor pulmonale caused by COPD revealed that oxygen consumption was not related to oxygen delivery in these patients. Tissue hypoxia was not so severe in stable state of COPD and remitting period of chronic cor pulmonale, although the oxygen delivery was decreased. The demand of oxygen consumption could still be met by means of compensatory mechanism in the body. Oxygen consumption was usually a little lower than normal (114.0 +/- 11.2 ml/min/M2) in COPD; while that in cor pulmonale a little higher than normal (145 +/- 32.4 ml/min/M2). There was significant difference (P less than 0.01). This could be used as one of the diagnostic criteria when combined with clinical data.