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SpotXplore: a Cytoscape plugin for visual exploration of hotspot expression in gene regulatory networks
Michel A Westenberg1, Jos B T M Roerdink, Oscar P Kuipers
1Department of Mathematics and Computer Science, Eindhoven University of Technology, Eindhoven, The Netherlands. m.a.westenberg@tue.nl
Unlabelled:
SpotXplore is a plugin for Cytoscape for extraction and visualization of differentially expressed subnetworks (hotspots) from gene networks. The hotspot-based visualization approach enables interactive exploration of regulatory interactions in differentially expressed gene sets, and it allows a researcher to explore gene expression in direct relation to the affected cellular gene network. The hotspots provide a view beyond the commonly used metabolic pathways and gene ontologies.
Availability:
http://www.win.tue.nl/∼mwestenb/spotxplore/.
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