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Updated: Sep 12, 2026

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
Published on: February 14, 2017
[Assessment of left ventricular diastolic function with color Doppler flow-comparison with pulsed Doppler and
1Second Affiliated Hospital, Hebei Medical College, Shijiazhuang.
Abstract:
To determine the relations among color Doppler echocardiographic, pulsed Doppler echocardiographic and radionuclide angiographic fractions of left ventricular filling, 37 patients were studied using the three techniques. Favorable correlations of the filling fractions were found between color Doppler (flow area/left ventricular cavity area) and radionuclide angiography both during early diastole (r = 0.94) and atrial systole (r = 0.90). The above results were better than those obtained from pulsed Doppler (E area/Total, A area/Total) and radionuclide angiography: during early diastole (r = 0.78) and atrial systole (r = 0.76). Color Doppler can be used as a new method for assessing the pattern of left ventricular filling.

