Occupational protein contact dermatitis: two case reports
Related Experiment Video
Updated: Jun 8, 2026

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
Published on: September 26, 2022
Joana Rocha1, Teresa Pereira, Artur Sousa-Basto
1Department of Dermatology, Braga Hospital, Apartado 2242, 4701-965 Braga, Portugal.
Abstract:
Protein contact dermatitis (PCD) is a contact dermatitis caused by high-molecular-weight proteins. This entity has been reported with increasing frequency, most commonly as occupational hand dermatitis in food handlers. Clinically, it is characterized by a chronic and recurrent dermatitis with erythema, scaling, and fissures with acute exacerbations occurring a few minutes after contact with offending allergen. We report two cases in confectioners who presented with chronic hand dermatitis.
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