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Updated: Jun 8, 2026
08:11
Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation
Published on: June 13, 2025
[Modular tumor prostheses of the humerus].
1Universitätsklinik für Orthopädie, Medizinische Universität, Allgemeines Krankenhaus der Stadt Wien, Währinger Gürtel 18-20, A-1090 Wien, Osterreich. philipp.funovics@meduniwien.ac.at
Der Orthopade
|September 24, 2010
Summary
Modular reconstruction of the humerus is a feasible treatment for bone tumors, restoring defects and offering good oncological outcomes. Functional results depend on bone and soft tissue loss, with revision rates at 23%.
Area of Science:
- Orthopedic oncology
- Musculoskeletal tumor surgery
- Reconstructive surgery
Context:
- The humerus is a frequent site for musculoskeletal tumors, necessitating reconstructive options.
- Modular prostheses offer an alternative to amputation, alongside APC (alloprosthetic) and biological reconstructions.
- Functional outcomes are significantly influenced by the degree of bone and soft tissue deficit.
Purpose:
- To evaluate the feasibility and outcomes of modular humeral reconstruction in cancer patients.
- To assess functional restoration and oncological safety of modular prostheses for humerus defects.
- To analyze revision rates and survival data for modular humeral reconstructions.
Summary:
- Modular humeral prostheses facilitate the restoration of bone defects following tumor resection.
- While anatomical shoulder prostheses have limitations, inverse designs and ligament repair implants may enhance shoulder function.
- Elbow prostheses generally provide satisfactory function.
- A study of 101 patients reported a 23% revision rate, with a median overall survival of 171 months and a 5-year survival of 53%.
Impact:
- Modular reconstruction presents a viable surgical option for humerus bone tumors, balancing oncological control with functional restoration.
- This approach can improve quality of life for cancer patients by preserving limb function.
- Understanding the factors affecting functional outcomes is crucial for patient selection and surgical planning.
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