[Modular tumor prostheses of the humerus]
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Updated: Jun 8, 2026

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation
Published on: June 13, 2025
1Universitätsklinik für Orthopädie, Medizinische Universität, Allgemeines Krankenhaus der Stadt Wien, Währinger Gürtel 18-20, A-1090 Wien, Osterreich. philipp.funovics@meduniwien.ac.at
Abstract:
The humerus is a common location of musculoskeletal tumors. Modular prostheses of the humerus, besides APC and biological reconstructions, allow restoration of resulting bone defects. The functional outcome is determined by the extent of bone and soft tissue loss. Anatomical shoulder prostheses have a limited abductor function, while shoulder function could be improved by an inverse prosthetic design and implants for ligament repair. Elbow prostheses provide satisfactory function. Our own results in 101 patients showed a 23% revision rate. The median overall survival was 171 months with an overall 5-year survival of 53%. With respect to good oncological outcomes modular reconstruction of the humerus is a feasible treatment option for cancer patients.
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