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Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.

Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic cells are...

Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...

Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...

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Related Experiment Video

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Targeted and Selective Treatment of Pluripotent Stem Cell-derived Teratomas Using External Beam Radiation in a Small-animal Model

Targeted and Selective Treatment of Pluripotent Stem Cell-derived Teratomas Using External Beam Radiation in a Small-animal Model

Published on: February 17, 2019

Embryonic stem cell-based therapeutics: balancing scientific progress and bioethics.

Ronald Chester¹, Robert Sackstein

¹New England School of Law, USA.

Health Matrix (Cleveland, Ohio : 1991)

|September 25, 2010

Summary

This summary is machine-generated.

Rapid advancements in embryonic stem (ES) cell technology are sparking bioethical discussions. This work presents a framework of ethical principles to guide scientists in developing ES cell therapies for human welfare.

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Area of Science:

Biomedical Science
Bioethics
Stem Cell Technology

Background:

Embryonic stem (ES) cell technologies are advancing rapidly.
These advancements necessitate a discussion on the ethical implications of ES cell research and application.
Existing ethical guidelines may not fully address the nuances of novel ES cell applications.

Purpose of the Study:

To present a comprehensive framework of bioethical principles.
To guide biomedical scientists and researchers in the ethical application of ES cell technologies.
To facilitate the responsible development of ES cell-based therapies for human welfare.

Main Methods:

Literature review of current bioethical principles.
Analysis of emerging ethical challenges in ES cell research.
Development of a structured ethical framework tailored to ES cell applications.

Main Results:

A proposed framework of bioethical principles is detailed.
The framework addresses key ethical considerations in ES cell research and therapy development.
Guidance is provided for navigating complex ethical dilemmas.

Conclusions:

The presented framework offers a robust guide for ethical conduct in ES cell research.
Adherence to these principles can foster public trust and responsible innovation.
This framework supports the advancement of human welfare through ethically sound ES cell therapies.