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Updated: Jun 8, 2026

Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA
Published on: February 1, 2019
Mechanism of bioactive transfer through liposomal bilayers
Behnoush Maherani1, Elmira Arab-Tehrani, Michel Linder
1École Nationale Supérieure d'Agronomie et des Industries Alimentaires, Institut National Polytechnique de Lorraine, 2 Avenue de la Forêt de Haye, 54501 Vandoeuvre les Nancy, France. behnoush.maherani@ensaia.inpl-nancy.fr
Abstract:
Today, liposomes are one of the most effective carriers systems employed in biological, pharmaceutical, medical and nutritional research. In order to optimize a liposomal formulation for the encapsulation, delivery and release of the entrapped material, it is necessary to study material passage through the lipidic and aqueous phases of the lipid vesicle. Towards this end, this article aims to review the mechanisms of bioactive transfer between different layers of a liposome and it also discusses about the bioactive release mechanism. Several methods of detection and observation of bioactive transfer in liposomal systems are presented.
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