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[Acute hepatic ischemia and cardiogenic shock in patients with dilated cardiomyopathy]
G Cardin1, M C Caporale, G Ramuscello
1Cattedra di Cardiologia, Università di Padova.
Insights
Elevated liver enzymes, including glutamic-oxalacetic transaminase, glutamic-pyruvic transaminase, and lactic-dehydrogenase, were observed in patients with congestive heart failure. This increase may stem from chronic stasis and acute liver ischemia.
Area of Science:
- Cardiology
- Hepatology
- Biochemistry
Background:
- Chronic congestive heart failure, particularly due to dilatative myocardiopathy, can lead to complex physiological changes.
- Acute decompensation, such as pulmonary edema and cardiogenic shock, presents significant clinical challenges.
- Liver function can be profoundly affected by severe cardiac compromise.
Abstract:
A sharp and unusually high increase in the serum of glutamic-oxalacetic and glutamic-pyruvic transaminase and of lactic-dehydrogenase accompanied the terminal events, acute pulmonary edema with cardiogenic shock, in 2 patients suffering from chronic congestive heart failure caused by dilatative myocardiopathy. Experimental and clinical data raises the possibility that the considerable enzymic increase may be due to the combined effect of chronic stasis and acute ischemia on the liver.