Related Experiment Video
Updated: Jun 8, 2026

12:18
Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
MRSA screening in the vascular day-case population.
Y Ahmad1, S Khandelwal, A M Nicolson
1Department of Vascular Surgery, Selly Oak Hospital, University Hospitals Birmingham NHS Foundation Trust, UK. yousif.ahmad@uhb.nhs.uk
Annals of the Royal College of Surgeons of England
|September 25, 2010
Summary
UK screening policy for methicillin-resistant Staphylococcus aureus (MRSA) in day-case surgery is not cost-effective. Selective screening of high-risk patients is recommended over universal MRSA screening.
Area of Science:
- Infectious Diseases
- Healthcare Policy
- Surgical Patient Care
Background:
- UK government prioritized methicillin-resistant Staphylococcus aureus (MRSA) screening for day-case surgical patients starting April 2009.
- New operational guidance mandated universal screening for this patient group.
- This study aimed to assess MRSA prevalence and screening effectiveness in vascular day-case surgery.
Purpose of the Study:
- Quantify MRSA-positive cases within the vascular day-case surgery population over one year.
- Identify risk factors associated with MRSA in this cohort.
- Evaluate the impact of new Department of Health (DH) guidance on screening rates.
Main Methods:
- Prospective review of electronic records and laboratory culture results.
- Identification of screened patients and MRSA isolation.
- Assessment for delayed discharges or MRSA-related complications.
Main Results:
- Six patients (2.1%) screened positive for MRSA; five were previously known MRSA carriers.
- Only 0.36% of patients were newly identified as MRSA-positive.
- Screening rates increased from 35% to 72.5% post-April 2009, aligning with DH guidance.
Conclusions:
- The assumptions justifying expanded MRSA screening policy are disputed.
- Universal MRSA screening for all vascular day-case admissions is not cost-effective.
- Recommend selective screening for patients with prior MRSA identification or high-risk factors.
Related Concept Videos
Clinical Significance of Antibiotic Resistance
Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...