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Updated: Jun 8, 2026
06:01
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Haemodynamic stroke: clinical features, prognosis, and management
Catharina J M Klijn1, L Jaap Kappelle
1Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, Netherlands. c.j.m.klijn@umcutrecht.nl
The Lancet. Neurology
|September 25, 2010
Summary
Haemodynamic stroke, caused by poor brain blood flow (hypoperfusion), differs from other ischemic strokes. Further research is needed to diagnose and treat this condition effectively.
Area of Science:
- Neurology
- Vascular Medicine
Background:
- Haemodynamic stroke results from hypoperfusion, unlike embolic or local vasculopathy strokes.
- Causes include systemic conditions (heart failure, hypotension) and severe carotid/vertebral artery obstruction.
Purpose of the Study:
- To differentiate haemodynamic stroke and transient ischaemic attack (TIA) from other stroke types based on clinical features.
- To highlight the role of cerebral perfusion investigations in diagnosis and prognosis.
- To address the lack of clinical trials in managing hypoperfusion-related ischaemic stroke.
Main Methods:
- Review of clinical features distinguishing haemodynamic stroke.
- Assessment of ancillary investigations for cerebral perfusion.
- Analysis of current management strategies and research gaps.
Main Results:
- Haemodynamic stroke presents unique clinical characteristics.
- Cerebral perfusion studies offer prognostic insights.
- Management is challenging due to limited clinical trial data.
Conclusions:
- Further research is essential to establish diagnostic criteria for haemodynamic stroke.
- Controlled studies are required to investigate effective treatment options for hypoperfusion-induced ischaemic stroke.
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