Association of a single nucleotide polymorphism in the CD209 (DC-SIGN) promoter with SARS severity
K Y K Chan1, M S Xu, J C Y Ching
1Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, SAR, China.
Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi
|September 25, 2010
Abstract
No abstract available in PubMed .
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Genome-wide Association Studies-GWAS
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
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Coronavirus
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Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...
