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Fungal flora in congenital dacryocystitis
1Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.
Abstract:
In this study, 86 eyes in 66 cases (20 bilateral) of congenital dacryocystitis were analysed for fungal growth. Fungi alone were isolated in 12 eyes (13.95%) and in 14 eyes (16.28%) together with bacteria--a total of 26 positive for fungus in 86 eyes (30.23%). These 26 eyes yielded on fungal culture a total of 28 isolates (in 2 eyes, another fungus was isolated on repeat culture). 11 types of fungi were cultured--C. albicans and A. niger accounted for 5 each out of 28. To the best of our knowledge this is the first report in the literature of fungal flora analysed in congenital dacryocystitis--not surprisingly, more than 30% of eyes were positive for fungus. Systemic studies of fungal flora in dacryocystitis are very few, and hardly any literature on this subject exists in congenital dacryocystitis. This study is an attempt to determine the frequency and clinical significance of fungi isolated from cases of congenital dacryocystitis.
Insights
Fungal infections are common in congenital dacryocystitis, affecting over 30% of affected eyes. This study details the types of fungi found, including Candida albicans and Aspergillus niger, in infants with this condition.
Area of Science:
- Ophthalmology
- Mycology
- Pediatrics
Background:
- Congenital dacryocystitis is a common condition in infants.
- The role of fungal infections in congenital dacryocystitis is not well-established.
- Limited research exists on fungal flora in congenital dacryocystitis.
Purpose of the Study:
- To determine the frequency of fungal isolation in congenital dacryocystitis.
- To identify the types of fungi involved in congenital dacryocystitis.
- To assess the clinical significance of fungal infections in this condition.
Main Methods:
- Analysis of fungal growth in 86 eyes from 66 cases of congenital dacryocystitis.
- Fungal cultures were performed on samples from affected eyes.
- Identification of fungal species isolated.
Main Results:
- Fungi were isolated in 30.23% of the analyzed eyes (26 out of 86).
- Fungi were found alone in 13.95% and with bacteria in 16.28% of eyes.
- Candida albicans and Aspergillus niger were the most frequently isolated fungi.
Conclusions:
- Fungal infections are a significant finding in congenital dacryocystitis.
- This study provides the first detailed analysis of fungal flora in congenital dacryocystitis.
- Further investigation into the clinical significance of these fungal isolates is warranted.