Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Actin Filament Depolymerization

Actin Filament Depolymerization

Actin filaments (F-actin) are composed of actin subunits. The dissociation of actin monomers can occur from either end of F-actin. The rate of dissociation is faster from the minus-end or the pointed end, where the actin subunits exist with a bound ADP, together known as ADP-actin. The depolymerization of F-actin is aided by proteins, including the actin-depolymerizing factor (ADF) and cofilin family of proteins, gelsolin, and glia maturation factor (GMF).
In F-actin, the ADF/cofilin proteins...

Pinching-off of Coated Vesicles

Pinching-off of Coated Vesicles

Vesicle budding is orchestrated by distinct cytosolic proteins such as adaptor proteins, coat proteins, and GTPases. To initiate vesicle budding, membrane-bending proteins containing crescent-shaped BAR domains bind to the lipid heads in the bilayer and distort the membrane to form a protein-coated vesicle bud. Adaptors proteins such as AP2 for clathrin-coated vesicles can nucleate on the deformed membrane. Finally, coat proteins such as clathrin or COPI and COPII assemble into a coat forming...

Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration

Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration

The rate of acid-catalyzed hydration of alkenes depends on the alkene's structure, as the presence of alkyl substituents at the double bond can significantly influence the rate.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Molecular Design in l-Glutamic Acid-Based Peptide Assembly Dynamics Driven by Carbodiimide-Fueled Reaction Cycle.

Biomacromolecules·2026

Same author

Combined effect of assisted Bioaugmentation and biochar incorporation on olive mill wastewater sludge composting.

Environmental pollution (Barking, Essex : 1987)·2025

Same author

A Survey of Preprocessing Techniques for Flow Cytometry Data in Classification Tasks.

IEEE transactions on computational biology and bioinformatics·2025

Same author

Mesoporous silica nanoparticles with an azobenzene gatekeeper as hypoxia-responsive nanocarriers for targeted doxorubicin delivery.

Drug delivery and translational research·2025

Same author

Minimalistic bis-triarylpyridinium cations: effective antimicrobials against bacterial and fungal pathogens.

RSC medicinal chemistry·2025

Same author

Silica-based optical chemosensors for rapid and reliable on-site detection of gamma-hydroxybutyrate in beverages and oral fluids.

Mikrochimica acta·2025

Search research articles

Related Experiment Video

Updated: Jun 8, 2026

Thermal Scanning Conductometry (TSC) as a General Method for Studying and Controlling the Phase Behavior of Conductive Physical Gels

Thermal Scanning Conductometry (TSC) as a General Method for Studying and Controlling the Phase Behavior of Conductive Physical Gels

Published on: January 23, 2018

Selective catechol-triggered supramolecular gel disassembly.

José A Sáez¹, Beatriu Escuder, Juan F Miravet

¹Departament de Química Inorgànica i Orgànica, Universitat Jaume I, Avda., Sos Baynat s/n, 12071 Castelló, Spain.

Chemical Communications (Cambridge, England)

|September 25, 2010

Summary

Supramolecular gels made from an isonicotinic acid derivative in toluene can be broken apart by adding catechol. This discovery shows a new way molecular recognition can cause gel disassembly, useful for drug delivery.

More Related Videos

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water

Published on: August 2, 2012

Related Experiment Videos

Last Updated: Jun 8, 2026

Thermal Scanning Conductometry (TSC) as a General Method for Studying and Controlling the Phase Behavior of Conductive Physical Gels

Thermal Scanning Conductometry (TSC) as a General Method for Studying and Controlling the Phase Behavior of Conductive Physical Gels

Published on: January 23, 2018

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water

Published on: August 2, 2012

Area of Science:

Supramolecular chemistry
Materials science
Chemical engineering

Background:

Supramolecular gels are advanced materials with potential applications in drug delivery.
Controlling the disassembly of these gels is crucial for targeted release mechanisms.

Purpose of the Study:

To investigate the selective disassembly of isonicotinic acid derivative-based supramolecular gels.
To explore the role of molecular recognition in gel-state transitions.

Main Methods:

Formation of supramolecular gels using an isonicotinic acid derivative in toluene.
Treatment of gels with catechol to observe disassembly.
Analysis of the molecular interactions driving the process.

Main Results:

Supramolecular gels in toluene were successfully and selectively disassembled by the addition of catechol.
This disassembly was directly linked to specific molecular recognition events between the gelator and catechol.

Conclusions:

The study demonstrates a novel mechanism for supramolecular gel disassembly driven by molecular recognition.
This finding offers a unique approach for developing stimuli-responsive materials for controlled drug release applications.