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Titanium tetrafluoride and dental caries: a systematic review
Rubiane Diógenes Alves1, Tatyana Maria Silva de Souza, Kenio Costa de Lima
1Federal University of Rio Grande do Norte, Natal, Brazil. rubiane.rn@ig.com.br
Titanium tetrafluoride shows potential as a caries preventive agent. However, limited high-quality clinical studies prevent definitive conclusions on its effectiveness against dental caries.
Area of Science:
- Dentistry
- Preventive Dentistry
- Cariology
Background:
- Dental caries remains a significant public health concern.
- Preventive strategies are crucial for caries management.
- Titanium tetrafluoride (TiF4) has been investigated for its potential anticariogenic properties.
Purpose of the Study:
- To systematically review the effectiveness of titanium tetrafluoride (TiF4) as a preventive or cariostatic agent against dental caries.
Main Methods:
- A systematic literature search was conducted in MEDLINE, LILACS, and BBO databases.
- Search terms included "titanium tetrafluoride" and relevant language filters.
- Out of 42 identified studies, only 2 in vivo studies met the selection criteria.
Main Results:
- Both selected studies indicated that titanium tetrafluoride was effective against caries.
- However, the clinical studies were of questionable quality and validity.
Conclusions:
- The current evidence is insufficient to definitively conclude the clinical effectiveness of titanium tetrafluoride against caries.
- Further high-quality clinical trials are needed to validate these findings.
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