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Published on: February 10, 2023
Unexpected MRI findings in clinically suspected Legg-Calvé-Perthes disease
Philip F Lobert1, Jonathan R Dillman, Peter J Strouse
1Department of Radiology, Section of Pediatric Radiology, C.S. Mott Children's Hospital/F3503, University of Michigan Health System, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-5252, USA.
Background:
In the setting of clinically suspected Legg-Calvé-Perthes (LCP) disease and negative/equivocal radiographs, contrast-enhanced MRI can be performed to confirm the diagnosis.
Objective:
To determine the frequency of unexpected causes of hip pain as identified by MRI in children with clinically suspected LCP disease and negative/equivocal radiographs.
Materials And Methods:
All pediatric contrast-enhanced MRI examinations of the pelvis and hips performed between January 2000 and February 2009 to evaluate for possible LCP disease in the setting of negative/equivocal radiographs were identified. MRI examinations performed to evaluate for secondary avascular necrosis were excluded. Imaging reports were retrospectively reviewed for unexpected clinically important causes of hip pain.
Results:
Thirty-six pediatric patients underwent contrast-enhanced MRI examinations for clinically suspected LCP disease in the setting of negative/equivocal radiographs. Twenty-two (61%) imaging studies were normal, while four (11%) imaging studies demonstrated findings consistent with LCP disease. Ten (28%) imaging studies revealed unexpected clinically important causes of hip pain, including nonspecific unilateral joint effusion and synovitis (n=7, juvenile chronic arthritis was eventually diagnosed in 3 patients), sacral fracture (n=1), apophyseal injury (n=1), and femoral head subluxation (n=1).
Conclusion:
MRI frequently reveals unexpected clinically important causes of hip pain in children with suspected LCP disease and negative/equivocal radiographs.
Insights
In children with suspected Legg-Calvé-Perthes (LCP) disease and unclear X-rays, MRI scans often reveal other serious hip pain causes. This imaging is crucial for accurate diagnosis when initial tests are inconclusive.
Area of Science:
- Pediatric Radiology
- Orthopedic Imaging
- Diagnostic Medicine
Background:
- Contrast-enhanced MRI is used to diagnose Legg-Calvé-Perthes (LCP) disease when radiographs are inconclusive.
- Children presenting with hip pain and equivocal radiographic findings require further diagnostic evaluation.
Purpose of the Study:
- To assess the frequency of unexpected, significant causes of hip pain identified by MRI in pediatric patients with suspected LCP disease.
- To evaluate the diagnostic yield of MRI in cases where initial radiographic assessment is negative or equivocal.
Main Methods:
- Retrospective review of pediatric contrast-enhanced pelvic and hip MRI reports (January 2000 - February 2009).
- Inclusion criteria: clinically suspected LCP disease, negative/equivocal radiographs, exclusion of secondary avascular necrosis.
- Analysis focused on identifying unexpected, clinically important causes of hip pain.
Main Results:
- Out of 36 pediatric patients, 22 (61%) had normal MRI findings.
- Four (11%) MRI studies showed findings consistent with LCP disease.
- Ten (28%) studies revealed unexpected causes: joint effusion/synovitis (n=7), sacral fracture (n=1), apophyseal injury (n=1), and femoral head subluxation (n=1).
Conclusions:
- MRI frequently identifies unexpected, clinically significant causes of hip pain in children with suspected LCP disease and negative radiographs.
- This highlights the value of MRI in diagnosing pediatric hip conditions beyond LCP disease.
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