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Updated: Jun 8, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Atrioventricular dissociation due to pheochromocytoma in a young adult
Steven E Haine1, Hielko P Miljoen, Ivan Blankoff
1University Hospital of Antwerp, Edegem, Belgium. Steven.Haine@uza.be
Insights
Pheochromocytoma, a rare tumor, can cause heart rhythm problems like atrioventricular dissociation. Treating this tumor can resolve these cardiac issues, potentially avoiding unnecessary procedures.
Area of Science:
- Cardiology
- Endocrinology
- Oncology
Background:
- Atrioventricular dissociation (AVD) is often associated with cardiac conditions but can also stem from noncardiac diseases.
- Supraventricular arrhythmias (SVAs) can be challenging to manage and diagnose, sometimes requiring invasive testing.
Observation:
- A patient presented with intermittent AVD and medically refractory SVAs, initially considered for pacemaker implantation.
- Electrophysiological testing did not induce the arrhythmias, suggesting an alternative etiology.
- The patient's symptoms were ultimately linked to a pheochromocytoma.
Findings:
- Surgical removal of the pheochromocytoma (left adrenalectomy) led to the complete resolution of both AVD and SVAs.
- This case highlights the potential for pheochromocytoma to manifest with cardiac rhythm disturbances.
Implications:
- Early recognition of pheochromocytoma is crucial for managing cardiac arrhythmias and AVD.
- Diagnosing and treating pheochromocytoma can prevent the need for potentially unnecessary cardiac interventions like electrophysiological testing and pacemaker implantation.
- This underscores the importance of considering noncardiac causes for complex cardiac presentations.
Abstract:
Atrioventricular dissociation can be a manifestation of an underlying noncardiac disease.We present a patient who underwent pacemaker implantation because of intermittent atrioventricular dissociation and medically untreatable supraventricular arrhythmias, which could not be induced by electrophysiological testing. The arrhythmias proved to be due to a pheochromocytoma. After left adrenalectomy, both the supraventricular arrhythmias and the atrioventricular dissociation disappeared. Adequate recognition and treatment of pheochromocytoma can reverse atrioventricular dissociation and may avoid unnecessary procedures such as electrophysiological testing and pacemaker implantation.
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