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Audiovestibular involvement in leprosy.

S K Awasthi1, G Singh, R K Dutta

  • 1Department of E.N.T., Armed Forces Medical College, Pune.

Indian Journal of Leprosy
|October 1, 1990
PubMed
Summary
This summary is machine-generated.

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Leprosy can cause hearing loss, particularly conductive hearing loss in BT leprosy and sensorineural hearing loss in LL leprosy with ENL reactions. Multidrug therapy showed no ototoxic effects on hearing.

Area of Science:

  • Otolaryngology
  • Infectious Diseases
  • Neurology

Background:

  • Leprosy, a chronic infectious disease, can affect various organ systems.
  • Audiovestibular involvement is a potential complication of leprosy, impacting patient quality of life.

Purpose of the Study:

  • To investigate audiovestibular function in leprosy patients.
  • To assess the ototoxic effects of multidrug therapy (MDT) for leprosy.

Main Methods:

  • Audiovestibular evaluation of 100 leprosy patients with different disease types.
  • Follow-up audiovestibular assessment of 50 new leprosy cases during MDT.

Main Results:

  • Conductive hearing loss found in 6 BT leprosy cases with middle ear infections.

Related Experiment Videos

  • Sensorineural hearing loss identified in 10 cases (6 LL, 2 BT, 2 pure neuritic), associated with ENL reactions in LL cases.
  • No vestibular involvement detected.
  • No audiovestibular dysfunction observed during MDT follow-up.

    • Conclusions:

    • Leprosy can lead to specific types of hearing loss, influenced by disease type and reactions.
    • Current multidrug therapy regimens appear safe regarding ototoxicity.