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Pasteurella multocida infective endocarditis: a case report
1Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Abstract:
A 17-year-old man presented with acute febrile illness with jaundice, embolic skin lesion, heart murmur, renal insufficiency and abnormal CSF. Pasteurella multocida was isolated from blood cultures. In spite of adequate antibiotic treatment for endocarditis of the mitral valve, he developed a fatal ruptured cerebral mycotic aneurysm. Post mortem examination revealed an atrial septal defect, vegetation at the anterior mitral leaflet, intraventricular, subarachnoid and intracerebral hemorrhage.
Insights
A severe Pasteurella multocida infection caused endocarditis and a fatal ruptured cerebral mycotic aneurysm in a young man. This case highlights the aggressive nature of this pathogen in adults, even with treatment.
Area of Science:
- Infectious Diseases
- Cardiology
- Neurology
Background:
- Pasteurella multocida is a bacterium typically associated with animal bites but can cause severe human infections.
- Endocarditis, an infection of the heart lining or valves, can lead to serious complications like embolic events and aneurysms.
- Congenital heart defects can predispose individuals to infective endocarditis.