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Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography
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The ANUBIS™ project.

Bernard Dallemagne1, Jacques Marescaux

  • 1Department of Digestive Surgery, University Hospital of Strasbourg & IRCAD-EITS, 1 Place de l’Hôpital, Strasbourg, France.

Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy
|September 28, 2010
PubMed
Summary
This summary is machine-generated.

The ANUBIS™ project advanced natural orifices transluminal endoscopic surgery (NOTES) by developing instruments and performing over 400 experimental procedures. This research successfully translated to the first human transvaginal and transgastric cholecystectomies.

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Area of Science:

  • Minimally Invasive Surgery
  • Surgical Innovation
  • Medical Robotics

Background:

  • Natural Orifices Transluminal Endoscopic Surgery (NOTES) presents a novel approach to minimally invasive procedures.
  • IRCAD-Strasbourg initiated the ANUBIS™ project to explore the feasibility and potential of NOTES.

Purpose of the Study:

  • To evaluate the concept and potential of NOTES.
  • To develop specialized instrumentation for NOTES procedures.
  • To facilitate the translation of NOTES research into clinical practice and provide education.

Main Methods:

  • Extensive experimental procedures (over 400) on various models including inanimate, ex-vivo, animal, and human cadavers.
  • Development of a novel therapeutic flexible endoscope (Anubiscope™).
  • Elaboration of techniques for viscerotomy closure.

Main Results:

  • Successful performance of the first human transvaginal cholecystectomy.
  • Subsequent performance of transgastric cholecystectomy.
  • Development and industrialization of specialized NOTES instrumentation.
  • Training of 500 participants in NOTES procedures.

Conclusions:

  • The ANUBIS™ project successfully demonstrated the potential of NOTES through rigorous experimental and clinical translation.
  • The project established a pathway for developing NOTES technology and providing essential training.