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Updated: Jun 8, 2026

Phenotypic and Functional Analysis of Activated Regulatory T Cells Isolated from Chronic Lymphocytic Choriomeningitis Virus-infected Mice
Published on: June 22, 2016
Regulatory T cells in central nervous system: in health and disease
Brenda Saenz1, Jesús Pérez-H, Anahí Chavarría
1Departamento de Inmunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, México.
Abstract:
Regulatory T cells participate in several immune responses including autoimmune reactions inducing self-tolerance, tumor immunity, transplantation tolerance and microbial infection. Nevertheless regulatory T cells actions seem to be different when they are in the central nervous system (CNS), since they interact with resident cells of the CNS, according to the particular conditions elicited in this compartment. This review focuses on the role of regulatory T cells in health, autoimmune and other CNS diseases, pointing out their interactions with resident CNS cells.
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