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Chronic cutaneous graft-versus-host disease manifesting as calcinosis cutis universalis on a background of widespread
Jeremy Man1, Michal Kalisiak, Iain W J Birchall
1Division of Dermatology, University of Alberta, Edmonton, Ab, Canada.
Background:
The cutaneous manifestations of graft-versus-host disease (GVHD) can be classified into acute and chronic forms. Acute GVHD is defined as a skin eruption that manifests within 100 days of transplantation, whereas chronic GVHD refers to cutaneous changes that appear 100 days or more posttransplantation.
Objective:
Although most chronic forms fall within lichenoid and sclerodermoid forms, there is a multitude of less common presentations. These include xerosis, follicular prominence, ichthyosis, and pityriasis rosea-like, eczematous, or psoriasiform lesions.
Conclusions:
We report a previously unreported manifestation of chronic cutaneous GVHD, specifically calcinosis cutis universalis on a background of sclerodermoid changes.
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