Related Experiment Video
Updated: Jun 8, 2026

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
Published on: May 19, 2020
Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (MAIVF): A comprehensive review
Selvin Sudhakar1, Asif Sewani, Mayank Agrawal
1Sparks Regional Medical Center, Fort Smith, Arkansas, USA. sudsel@yahoo.com
Abstract:
Pseudoaneurysm in the region of the fibrous body between the mitral and aortic valve, the mitral-aortic intervalvular fibrosa (MAIVF), is a rare complication. The authors provide a comprehensive review of all relevant English-language articles published from 1966 to December 2009. Pseudoaneurysm of the MAIVF was identified in 88 patients in the medical literature and one from the authors' institution (total reported cases, 89). Endocarditis and aortic valve surgery were the most frequently associated causative factors. Symptoms and signs of infection, chest pain, heart failure or shortness of breath, and cerebrovascular accidents accounted for 77% of clinical presentations. The formation of a fistulous tract, coronary artery compression, and death were important described complications. Patients with ring abscesses in the MAIVF region and those with prosthetic aortic valves and histories of endocarditis are at higher risk for developing pseudoaneurysm of the MAIVF. Transesophageal echocardiography was able to identify all cases in which it was used. Surgical correction is the treatment of choice.
Insights
Mitral-aortic intervalvular fibrosa pseudoaneurysms are rare but serious cardiac complications. Early detection and surgical correction are crucial for managing this condition, often linked to endocarditis or valve surgery.
Area of Science:
- Cardiology
- Cardiac Surgery
- Medical Imaging
Background:
- Pseudoaneurysms in the mitral-aortic intervalvular fibrosa (MAIVF) are rare cardiac complications.
- These can arise from various factors, including endocarditis and aortic valve surgery.
Purpose of the Study:
- To conduct a comprehensive review of pseudoaneurysms in the MAIVF region.
- To analyze causative factors, clinical presentations, complications, and management strategies.
Main Methods:
- Systematic literature review of English-language articles from 1966 to December 2009.
- Analysis of 89 reported cases, including one from the authors' institution.
Main Results:
- Endocarditis and aortic valve surgery were the most frequent causes.
- Common presentations included infection, chest pain, heart failure, and cerebrovascular accidents.
- Transesophageal echocardiography demonstrated high diagnostic accuracy.
Conclusions:
- Patients with ring abscesses or prosthetic valves and endocarditis history are at higher risk.
- Surgical correction is the recommended treatment for MAIVF pseudoaneurysms.
Related Concept Videos
Aneurysm I: Introduction
Mitral Valve Prolapse I: Introduction
Mitral Stenosis I: Introduction
Mitral Regurgitation I: Introduction
Mitral Stenosis III: Medical Management
Mitral Regurgitation III: Medical Management

