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Updated: Jun 8, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
[Evolution of adherence to guidelines for prevention of group B streptococcal infections]
M Cortet1, C Dupont, V Prunaret-Julien
1Service de gynécologie-obstétrique, hospices civils de Lyon, hôpital de la Croix-Rousse, 103, grande rue de la Croix-Rousse, 69004 Lyon cedex 04, France. marion.cortet@chu-lyon.fr
Insights
Caregiver education improved adherence to the neonatal group B streptococcal infection prevention program. This led to increased screening and surveillance, with no neonatal infections observed in the study period.
Area of Science:
- Obstetrics and Gynecology
- Neonatal Care
- Infectious Disease Prevention
Context:
- Group B Streptococcus (GBS) poses a significant risk for neonatal infections.
- Effective prevention programs are crucial for reducing GBS transmission.
- The Aurore network implemented a GBS prevention program with evolving strategies.
Purpose:
- To evaluate the implementation changes of the neonatal GBS infection prevention program within the Aurore network from 2004 to 2009.
- To assess the program's effectiveness in reducing neonatal GBS infections.
Summary:
- A cross-sectional study compared GBS prevention program implementation in 2004 and 2009.
- Vaginal swab rates increased significantly (91.1% to 96.3%), while GBS positivity rates slightly increased (10.2% to 14.2%).
- Antibiotic use remained stable, but neonatal surveillance significantly improved, resulting in zero observed neonatal infections.
Impact:
- Enhanced caregiver sensitization correlates with improved program adherence.
- The study demonstrates the success of targeted interventions in GBS prevention.
- Findings support the widespread adoption of similar GBS prevention strategies in maternity units.
Objective:
Assess the evolution in implementation of neonatal group B streptococcal infections prevention program in the Aurore network, between 2004 and 2009.
Patients And Methods:
A cross-sectional study was conducted during one week in the whole maternity units of the Aurore network about implementation of the neonatal streptococcal infection prevention program. Deliveries occurring after 37 weeks of gestation were included. Every stage required by the prevention program was registered for every delivery. Results obtained during this study were compared with those obtained in 2004.
Results:
Seven hundred and forty-four patients were included in 2004 and 618 in 2009. Vaginal swab rate was 96.3% in 2009 and 91.1% in 2004 (P<0.001), with a positive rate of 10.2 and 14.2%, respectively (P=0.041). Antibiotic infusion rates during delivery did not increase significantly. Clinical and biological surveillance of exposed newborns was significantly increased (P<0.001). No neonatal infection was observed during the study among newborns included in the program.
Conclusion:
Sensitization of caregivers about neonatal streptococcal infection prevention seems to be efficient to increase the application of the prevention program written by the Aurore network.
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