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Updated: Jun 8, 2026

In vivo Reprogramming of Adult Somatic Cells to Pluripotency by Overexpression of Yamanaka Factors
12:12

In vivo Reprogramming of Adult Somatic Cells to Pluripotency by Overexpression of Yamanaka Factors

Published on: December 17, 2013

Regulation of somatic cell reprogramming through inducible mir-302 expression

Shi-Lung Lin1, Donald C Chang, Chun-Hung Lin

  • 1WJWU and LYNN Institute for Stem Cell Research, Santa Fe Springs, CA 90670, USA. shilungl@mirps.org

Nucleic Acids Research
|September 28, 2010
PubMed
Summary

Induced microRNA-302 (miR-302) expression reprograms human hair follicle cells into induced pluripotent stem cells by targeting epigenetic regulators. This process enhances global DNA demethylation, linking zygotic and somatic cell reprogramming.

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