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Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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Prostate Cancer Working Group report.

Mikio Namiki1, Hideyuki Akaza, Sang Eun Lee

  • 1Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Takara-machi, Kanazawa City, Ishikawa 920-8640, Japan. namiki1@kenroku.kanazawa-u.ac.jp

Japanese Journal of Clinical Oncology
|September 28, 2010
PubMed
Summary

Prostate cancer is rising in Asia due to lifestyle changes. Early detection via prostate-specific antigen (PSA) screening and prevention strategies are crucial for Asian populations to combat increasing mortality rates.

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Area of Science:

  • Oncology
  • Public Health
  • Epidemiology

Background:

  • Prostate cancer incidence is rising in Asian countries, linked to westernized lifestyles.
  • Unlike Western nations, Asian countries face increasing prostate cancer mortality due to a high prevalence of advanced-stage diagnoses.
  • Early detection and prevention are critical for Asian populations, yet prostate-specific antigen (PSA) screening rates remain low.

Purpose of the Study:

  • To highlight the urgent need for early prostate cancer detection and comprehensive prevention strategies in Asia.
  • To emphasize the importance of increasing prostate-specific antigen (PSA) screening rates to reduce mortality.
  • To explore the potential role of isoflavones in prostate cancer prevention and the efficacy of hormonal therapy in Asian patients.

Main Methods:

  • Review of current prostate cancer incidence, mortality, and screening trends in Asian countries compared to Western nations.
  • Analysis of factors contributing to advanced-stage diagnosis and mortality in Asia.
  • Discussion of potential preventive measures, including soy isoflavone consumption and the effectiveness of hormonal therapy.

Main Results:

  • Prostate cancer incidence is increasing in Asia, with a high proportion of advanced-stage cases leading to rising mortality.
  • Low prostate-specific antigen (PSA) screening rates in Asia contribute to late diagnoses and poorer outcomes.
  • Hormonal therapy may be more effective in Asian populations, suggesting a need for guideline adjustments.

Conclusions:

  • Increased prostate-specific antigen (PSA) screening and robust cancer prevention strategies are essential for Asian men.
  • Further research, including large multinational studies, is needed to confirm the preventive effects of isoflavones and optimize treatment protocols.
  • Collaborative efforts among Asian countries are vital for advancing prostate cancer research and clinical practice.