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A death due to self-administered fentanyl.

A K Chaturvedi1, N G Rao, J R Baird

  • 1Office of the State Toxicologist, North Dakota State University College of Pharmacy, Fargo 58105.

Journal of Analytical Toxicology
|November 1, 1990
PubMed
Summary

A health care professional died from a fentanyl overdose after self-administering the drug. Toxicological analysis confirmed high fentanyl levels in tissues, indicating overdose as the primary cause of death.

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Area of Science:

  • Forensic Toxicology
  • Clinical Chemistry
  • Pharmacology

Background:

  • A case study involving a deceased health care professional with a history of substance abuse.
  • Investigation into a fatality potentially linked to self-administered substances.

Observation:

  • A syringe with red fluid was discovered at the scene.
  • Autopsy revealed pulmonary congestion, hemorrhage, aspiration of gastric contents, and congestion in the liver and kidneys.

Findings:

  • Fentanyl was detected in syringe fluid and urine, along with diazepam/oxazepam.
  • Gas chromatography quantified fentanyl in serum, blood, and various tissues at elevated levels.
  • Fentanyl concentration in syringe contents was 2,800 µg/L, consistent with overdose.

Implications:

  • This case highlights the lethal potential of self-administered fentanyl, even in health care professionals.
  • Confirms fentanyl as the primary cause of death, underscoring the need for vigilance in substance abuse cases.
  • Demonstrates the utility of comprehensive toxicological analysis in determining cause of death.

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