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The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool
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Physical activity and irreversible disability in multiple sclerosis.

Robert W Motl1

  • 1Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 906 S Goodwin Ave, Urbana, IL 61801, USA. robmotl@uiuc.edu

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Physical activity may influence disability progression in multiple sclerosis (MS). This review emphasizes studying physical activity

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Area of Science:

  • Neurology
  • Rehabilitation Science
  • Clinical Research

Background:

  • Multiple sclerosis (MS) is a progressive neurological disorder characterized by increasing disability.
  • Physical activity has been identified as a factor associated with disability levels in MS patients.
  • Existing research often overlooks the impact of physical activity in later stages of MS.

Purpose of the Study:

  • To review the role of physical activity in the progression of disability in multiple sclerosis.
  • To provide a rationale for investigating physical activity's influence in the second stage of MS.
  • To highlight the need for research in understudied MS populations.

Main Methods:

  • Literature review of existing research on physical activity and disability in multiple sclerosis.
  • Analysis of studies focusing on different stages of MS disability.
  • Identification of research gaps concerning physical activity in advanced MS.

Main Results:

  • Physical activity is a recognized correlate of disability in multiple sclerosis.
  • Previous studies predominantly included individuals with minimal MS-related disability.
  • A gap exists in understanding physical activity's influence during later stages of MS.

Conclusions:

  • Physical activity warrants consideration as a significant factor influencing disability in multiple sclerosis.
  • Future research should focus on the impact of physical activity in individuals with more advanced MS.
  • Understanding this relationship can inform interventions to manage MS progression.