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Updated: Jun 8, 2026

Discovery and Synthesis Optimization of Isoreticular Al(III) Phosphonate-Based Metal-Organic Framework Compounds Using High-Throughput Methods
Published on: October 6, 2023
Isoreticular synthesis and modification of frameworks with the UiO-66 topology
Sergio J Garibay1, Seth M Cohen
1Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093-0358, USA.
Abstract:
Amino, bromo, nitro, and naphthalene functionalized UiO-66 metal-organic frameworks have been synthesized through reticular chemistry. UiO-66-NH(2) is shown to be suitable for postsynthetic modification with a variety of anhydrides to generate new, functionalized frameworks.
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