Related Experiment Video
Updated: Jun 8, 2026
07:30
Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
Published on: March 7, 2018
Positively-charged gold nanoparticles as peroxidase mimic and their application in hydrogen peroxide and glucose
1Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Materials Science, Shaanxi Normal University, Xi'an 710062, P.R. China.
Chemical Communications (Cambridge, England)
|September 28, 2010
Abstract:
Positively-charged gold nanoparticles possess intrinsic peroxidase-like activity, and can catalyze oxidation of the peroxidase substrate 3,3,5,5-tetramethylbenzidine (TMB) by H(2)O(2) to develop a blue color in aqueous solution, thus providing a simple approach to colorimetric detection of H(2)O(2) and glucose.
Related Concept Videos
01:10Amperometry: Overview
Amperometry is a technique commonly used to measure the concentration of specific analytes in a solution by monitoring the electric current generated during an electrochemical reaction. It involves applying a constant potential between a working electrode and a reference electrode to measure the resulting current, which is proportional to the concentration of the analyte. The Clark oxygen electrode operates based on this principle of amperometry. It consists of a cathode and an anode enclosed...
01:20Immunogold Electron Microscopy
Immunoelectron microscopy utilizes immunogold labeling of endogenous proteins with specific antibodies to detect and localize these proteins in cells and tissues. The procedure provides insights into the distribution and quantification of protein under different stimulation conditions offering clues about their functions. Conjugating highly electron-dense gold particles with primary or secondary antibodies allow antigen detection on and within cells, with high resolution and specificity.