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Updated: Jun 8, 2026
Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
Published on: March 29, 2018
[Localization of enamelin in developing rat incisor by immunofluorescence]
1Department of Stomatology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, Hospital of Stomatology, Tongji University, Shanghai 200072, China. tanlionone@yahoo.com.cn
Purpose:
To investigate the expression of enamelin in developing rat incisor.
Methods:
Immunofluorescence staining for the specimens of developing rat incisor was used to localize the expression of enamelin.
Results:
Enamelin was not detected at the proliferation phase, and early differentiation phase in preameloblasts. At the advanced differentiation phase, enamelin expressed weakly in ameloblasts and odotoblasts. At the early maturation phase enamelin was detected in ameloblasts and odotoblasts. Enamelin expressed strongly in ameloblasts and enamel matrix but strongly in odotoblasts at the intermediate maturation phase and weakly at the advanced maturation phase. Enamelin was not found in the other stages and position.
Conclusion:
Enamelin,involved in enamel and dentin matrix formation, may play an important role in signal transduction of matrix formation. Supported by Project of the "Tenth-Five Year" Science Support Plans and Project "211" of Tongji University (Grant No.1504102011).
