Related Experiment Video
Updated: Jun 8, 2026

A Mouse Model of Intestinal Partial Obstruction
Published on: March 5, 2018
Rectal obstruction by a giant pharmacobezoar composed of magnesium oxide: report of a case
Yoshinobu Shigekawa1, Yasuhito Kobayashi, Takashi Higashiguchi
1Department of Surgery, Wakayama Rosai Hospital, Wakayama, Japan.
Abstract:
This report presents the rare case of a 75-year-old woman who developed a rectal obstruction caused by a pharmacobezoar, following the long-term ingestion of magnesium oxide cathartics for constipation. She was admitted to the hospital with lower abdominal pain and nausea. Abdominal computed tomography and magnetic resonance imaging showed that a huge calcified mass caused the rectal obstruction. A divided sigmoid colostomy was performed to relieve her symptoms, a colonoscopy from the distal stoma delineated a huge bezoar in the rectum, and thereafter she underwent an enterotomy. Magnesium oxide was detected in an analysis of a sample from this bezoar. Phamacobezoars resulting from laxatives or cathartics have rarely been reported. The current report showed a rectal obstruction caused by a pharmacobezoar composed primarily of magnesium oxide.
Related Concept Videos
Intestinal Obstruction I: Introduction
Intestinal Obstruction II: Pathophysiology
Pyloric Obstruction
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Drugs for Treatment of Constipation-Predominant IBS
Lower GI Series: Barium Enema
Procedure Details
The examination begins by inserting a lubricated rectal tube into the patient's rectum to administer a radiopaque barium solution. The barium flow is carefully...
