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Chronic Salmonella Infection Induced Intestinal Fibrosis

Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

Yersinia pseudotuberculosis colitis presented with severe gastrointestinal bleeding.

Ertan Bülbüloğlu¹, Harun Ciralik, Bülent Kantarçeken

¹Department of General Surgery, Kahramanmaraş Sütçü Imam University, School of Medicine, Kahramanmaraş, Turkey. ertanbulbuloglu@yahoo.com

The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology

|September 28, 2010

Summary

Yersinia pseudotuberculosis can cause severe lower gastrointestinal bleeding in adults. This case highlights the importance of considering this rare bacterial infection in patients with unexplained gastrointestinal hemorrhage.

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Area of Science:

Gastroenterology
Infectious Diseases
Pathology

Background:

Yersinia pseudotuberculosis is a bacterial pathogen that can cause various gastrointestinal illnesses.
Severe lower gastrointestinal bleeding is an uncommon but serious manifestation of Yersinia pseudotuberculosis infection.

Observation:

A 25-year-old male presented with fever, vomiting, body aches, and massive lower gastrointestinal bleeding.
Emergency explorative laparotomy revealed localized wall thickening and ulcers in the cecum.
Histological examination showed transmural inflammation and non-caseation granulomas in mesenteric lymph nodes.

Findings:

Yersinia pseudotuberculosis infection was confirmed by positive serology.
The patient underwent a right hemicolectomy and was treated with gentamicin.
Histopathology revealed characteristic inflammatory changes consistent with Yersinia infection.

Implications:

This case underscores the importance of considering Yersinia pseudotuberculosis in the differential diagnosis of massive lower gastrointestinal bleeding.
Early recognition and appropriate antibiotic treatment are crucial for favorable outcomes.
Further research into the pathogenesis of severe gastrointestinal bleeding caused by Yersinia pseudotuberculosis is warranted.