Hb Baden: structural and functional characterization

Osheiza Abdulmalik1, Martin K Safo, Steven H Seeholzer

  • 1Department of Pediatrics (Hematology), University of Pennsylvania School of Medicine, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA.

Summary

Hb Baden, a rare hemoglobin variant, shows instability and high oxygen affinity despite normal health in a heterozygote. This finding impacts understanding of hemoglobinopathies and beta-globin structure.