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Analysis of hypotensive compounds occurring in complex agents.

Mariusz Stolarczyk¹, Anna Maślanka, Anna Apola

¹Jagiellonian University,Collegium Medicum, Department of Inorganic and Analytical Chemistry, Medyczna 9, 30-688 Kraków, Poland. mstolar@cm-uj.krakow.pl

Acta Poloniae Pharmaceutica

|September 30, 2010

Summary

This review covers analytical methods for hypotensive complex agents, including spectrophotometry, chromatography (GC, HPLC, LC-MS), and electroanalytical techniques (DPP, ASV, CV). It summarizes publications from 1995-2009.

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Area of Science:

Analytical Chemistry
Pharmacology

Background:

Hypotensive complex agents require precise analytical methods for quality control and research.
A comprehensive overview of analytical techniques is crucial for researchers in this field.

Purpose of the Study:

To review and summarize analytical methods used for hypotensive complex agents.
To cover publications from 1995 to 2009.

Main Methods:

Spectrophotometry and derivative spectrophotometry.
Chromatographic techniques: gas chromatography (GC), high-performance liquid chromatography (HPLC), thin-layer chromatography (TLC), high-performance thin-layer chromatography (HPTLC), liquid chromatography-tandem mass spectrometry (LC-MS), microchip electrophoresis (MCE), and capillary electrophoresis (CE).
Electroanalytical methods: differential pulse polarography (DPP), cathodic stripping voltammetry (CSV), anodic stripping voltammetry (ASV), differential pulse voltammetry (DPV), cyclic voltammetry (CV), stripping voltammetry (SV), square wave voltammetry (SWV), and square wave polarography (SWP).

Main Results:

The review systematically categorizes and describes various analytical techniques.
It highlights the application of these methods in the analysis of hypotensive complex agents.
The selected methods offer diverse approaches for quantification and characterization.

Conclusions:

A wide array of analytical methods are available for the analysis of hypotensive complex agents.
The choice of method depends on the specific agent and analytical requirements.
This review provides a valuable resource for selecting appropriate analytical strategies.