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Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...

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Updated: Jun 8, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

Fetal behavioral teratology.

Gerard H A Visser1, Eduard J H Mulder, F F Tessa Ververs

  • 1Department of Obstetrics, University Medical Center, Lundlaan 6, Utrecht, The Netherlands. g.h.a.visser@umcutrecht.nl

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|September 30, 2010
PubMed
Summary
This summary is machine-generated.

Ultrasound reveals how fetal motor behavior reflects central nervous system development. Abnormalities in fetal movements and behavior can indicate health issues during pregnancy.

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Area of Science:

  • Neuroscience
  • Developmental Biology
  • Prenatal Medicine

Background:

  • Fetal motor behavior, observable via ultrasound, offers direct insight into the developing fetal central nervous system.
  • Understanding fetal movements is crucial for assessing neurodevelopmental health.
  • Previous research indicates potential links between maternal health and fetal neurodevelopment.

Purpose of the Study:

  • To review existing ultrasound studies on fetal motor behavior.
  • To examine how various factors impact the emergence and characteristics of fetal movements.
  • To explore the relationship between fetal motor patterns and neurodevelopmental outcomes.

Main Methods:

  • Systematic review of ultrasound studies focusing on fetal motor behavior.
  • Analysis of data on the timing, quality, and quantity of fetal movements.
  • Evaluation of fetal behavioral state development in relation to maternal and environmental factors.

Main Results:

  • Documented changes in the initial appearance of fetal movements.
  • Observed alterations in the quality and/or quantity of fetal movements.
  • Identified disturbances in the development of fetal behavioral states linked to maternal conditions and teratogens.

Conclusions:

  • Ultrasound assessment of fetal motor behavior is a valuable tool for evaluating fetal neurodevelopment.
  • Maternal diseases and exogenous teratogens can negatively impact fetal motor development and behavioral states.
  • Further research is warranted to fully elucidate the predictive value of fetal motor behavior in prenatal diagnostics.