Related Experiment Video
Updated: Jun 8, 2026

Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays
Published on: November 12, 2012
Natural parameter values for generalized gene adjacency
1Department of Mathematics and Statistics, University of Ottawa, 585 King Edward Avenue, Ottawa, Ontario, Canada.
Abstract:
Given the gene orders in two modern genomes, it may be difficult to decide if some genes are close enough in both genomes to infer some ancestral proximity or some functional relationship. Current methods all depend on arbitrary parameters. We explore a class of gene proximity criteria and find two kinds of natural values for their parameters. One kind has to do with the parameter value where the expected information contained in two genomes about each other is maximized. The other kind of natural value has to do with parameter values beyond which all genes are clustered. We analyze these using combinatorial and probabilistic arguments as well as simulations.
More Related Videos
10:44Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline
Published on: December 7, 2021
07:20Maintaining Biological Cultures and Measuring Gene Expression in Aphis nerii: A Non-model System for Plant-insect Interactions
Published on: August 31, 2018
Related Concept Videos
Combinatorial Gene Control
The expression of more than 30,000 genes is controlled by approximately 2000-3000 transcription factors. This is possible because a single transcription factor can recognize more than one regulatory sequence. The specificity in gene...
Hardy-Weinberg Principle
Mutation, Gene Flow, and Genetic Drift
Genetic Variation
Genes exist in different versions called alleles, which...
Multiple Allele Traits
Multiple Allele Traits