Related Experiment Video

Updated: Jun 8, 2026

Subconjunctival Administration of Adeno-associated Virus Vectors in Small Animal Models
06:16

Subconjunctival Administration of Adeno-associated Virus Vectors in Small Animal Models

Published on: March 16, 2022

AAV-mediated gene therapy for the treatment of retinal diseases

Fabienne Rolling

    Current Gene Therapy
    |September 30, 2010
    PubMed
    Abstract

    No abstract available in PubMed .

    More Related Videos

    Limbal Approach-Subretinal Injection of Viral Vectors for Gene Therapy in Mice Retinal Pigment Epithelium
    06:48

    Limbal Approach-Subretinal Injection of Viral Vectors for Gene Therapy in Mice Retinal Pigment Epithelium

    Published on: August 7, 2015

    Digital Droplet PCR Method for the Quantification of AAV Transduction Efficiency in Murine Retina
    09:50

    Digital Droplet PCR Method for the Quantification of AAV Transduction Efficiency in Murine Retina

    Published on: December 25, 2021

    Related Experiment Videos

    Last Updated: Jun 8, 2026

    Subconjunctival Administration of Adeno-associated Virus Vectors in Small Animal Models
    06:16

    Subconjunctival Administration of Adeno-associated Virus Vectors in Small Animal Models

    Published on: March 16, 2022

    Limbal Approach-Subretinal Injection of Viral Vectors for Gene Therapy in Mice Retinal Pigment Epithelium
    06:48

    Limbal Approach-Subretinal Injection of Viral Vectors for Gene Therapy in Mice Retinal Pigment Epithelium

    Published on: August 7, 2015

    Digital Droplet PCR Method for the Quantification of AAV Transduction Efficiency in Murine Retina
    09:50

    Digital Droplet PCR Method for the Quantification of AAV Transduction Efficiency in Murine Retina

    Published on: December 25, 2021

    Related Concept Videos

    Gene Therapy00:59

    Gene Therapy

    Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...
    Gene Therapy00:59

    Gene Therapy

    Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...

    Articles linked to this work by shared authors, journal, and citation graph.

    Safety and Long-Term Efficacy of AAV4 Gene Therapy in Patients with RPE65 Leber Congenital Amaurosis.

    Molecular therapy : the journal of the American Society of Gene Therapy·2017

    Safety and Efficacy of Regional Intravenous (RI) Versus Intramuscular (IM) Delivery of rAAV1 and rAAV8 to Nonhuman Primate Skeletal Muscle.

    Molecular therapy : the journal of the American Society of Gene Therapy·2017

    Vitrectomy Before Intravitreal Injection of AAV2/2 Vector Promotes Efficient Transduction of Retinal Ganglion Cells in Dogs and Nonhuman Primates.

    Human gene therapy methods·2016

    AAV-mediated Gene Therapy Halts Retinal Degeneration in PDE6β-deficient Dogs.

    Molecular therapy : the journal of the American Society of Gene Therapy·2016

    Transgene regulation using the tetracycline-inducible TetR-KRAB system after AAV-mediated gene transfer in rodents and nonhuman primates.

    PloS one·2014

    Immuno-histochemical analysis of rod and cone reaction to RPE65 deficiency in the inferior and superior canine retina.

    PloS one·2014

    Advances in the Application of Adenine Base Editor (ABE) in Biology and Medicine: Prospects and Challenges.

    Current gene therapy·2026

    siRNA and mRNA Therapeutics: A Comprehensive Review of Mechanisms, Delivery Strategies, Clinical Applications, and Future Directions in Precision Pharmacology.

    Current gene therapy·2026

    Efficacy and Safety of Immune Checkpoint Inhibitors for Recurrent or Metastatic Cervical Cancer: A Systematic Review and Meta-Analysis.

    Current gene therapy·2026

    Integration of Single-Cell Transcriptomics and Network-Based Machine Learning Identifies Bone Marrow Mesenchymal Stem Cell-Associated Candidate Biomarkers and Exploratory Immune Correlates in Osteoarthritis.

    Current gene therapy·2026

    The TRH-TRHR Axis Acts as a Metabolic Checkpoint for Ammonia Tolerance in AML: Therapeutic Targeting via Imiquimod and Itraconazole.

    Current gene therapy·2026

    ZBTB33/RBM15 Axis Upregulates MACC1 to Promote the Malignant Progression of Colorectal Cancer.

    Current gene therapy·2026

    Transforming therapeutics through biomaterials: A comprehensive insight into biomaterials' role in effective drug delivery and healthcare advancement.

    Biomaterials translational·2026

    Modifiable Transdiagnostic Risk and Protective Factors as Potential CBT Augmentation Targets for Eating Disorders: An Updated Umbrella Review.

    The International journal of eating disorders·2026

    Long-Term Survival of Patients Undergoing Transcatheter Aortic Valve Implantation Under General Anesthesia Versus Monitored Anesthesia Care.

    Journal of cardiothoracic and vascular anesthesia·2026

    Distinct pattern of reported adverse event with SGLT2 inhibitors in heart failure: A pharmacovigilance study using VigiBase data.

    Therapie·2026

    Synthesis and characterization of l-arginine-grafted chitosan nanoparticles for intranasal Dasatinib delivery and brain targeting.

    Nanomedicine : nanotechnology, biology, and medicine·2026

    Piceatannol loaded mesenchymal stem cells derived exosomes for cutaneous regenerative treatment of psoriasis-like symptoms in imiquimod-induced mice model: Exosomal hydrogel impact via targeting of JAK3/STAT3 signaling.

    Nanomedicine : nanotechnology, biology, and medicine·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us