Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Sleep Apnea

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...

Other Pulmonary Disorders

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.

Alterations in Respiration II

Alterations in Respiration II

There are numerous types of normal and abnormal respiration. Based on ventilatory movements, breathing patterns are classified as regular, deep, or shallow. Examples include Biot's breathing, Cheyne-Stokes respiration, Kussmaul's breathing, hyperventilation, and hypoventilation. Each pattern is clinically significant and aids in evaluating patients.
In Biot's breathing, the respiratory rate and depth are irregular, alternating between periods of deep gasping and apnea. Common causes include...

Sleep-Wake Cycles

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:

Disorders of the Autonomic Nervous System

Disorders of the Autonomic Nervous System

The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's phenomenon, is a...

Circadian Rhythms and Gene Regulation

Circadian Rhythms and Gene Regulation

The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent years,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Sleep and Mental Health Among Employed Adults in Beijing, China.

Annals of the New York Academy of Sciences·2026

Same author

Ru-SATED scale and Sleep Health Index: A systematic review of two leading multidimensional sleep health measures and frameworks across the globe.

Sleep medicine reviews·2026

Same author

The effect of caffeinated beverage consumption on the relationship between sleep quality and major adverse cardiovascular events: Sleep Heart Health Study.

Sleep advances : a journal of the Sleep Research Society·2026

Same author

Banff 2024 Pancreas Transplantation Report: Diagnosis and impact of chronic active T cell-mediated allograft rejection and re-evaluation of the indeterminate category with utilization of leukocyte immunostains in biopsies with ambiguous findings.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2026

Same author

Obesity Management in End-Stage Kidney Disease: Pathways to Improve Kidney Transplant Access.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2026

Same author

Perirenal Adipose Tissue may be an Important Predictor of Adverse Kidney Outcomes in Living Kidney Donors.

Kidney international reports·2026

Same journal

Response to the Letter to the Editor Regarding "Comparative Evaluation of Risk Scores for Predicting Postoperative Pulmonary Complications".

Respiratory care·2026

Same journal

Respiratory Muscle Dysfunction in Stable COPD: A Multimodal Assessment of Diaphragmatic and Cough-Related Impairment.

Respiratory care·2026

Same journal

Flow Asynchronies During Pressure Support Ventilation in Children: A Bench Model Study.

Respiratory care·2026

Same journal

Inspiratory Effort Assessment Using the Occlusion Pressure-Derived Tension-Time Index.

Respiratory care·2026

Same journal

Clinical Usage of High-Flow Nasal Cannula Across Disease Categories and Care Settings: A Nationwide Cohort Study in Japan.

Respiratory care·2026

Same journal

Efficacy of Mechanical Insufflation-Exsufflation Devices as Analyzed in Lung Models: Systematic Review and Network Meta-Analysis of Peak Expiratory Flow Data.

Respiratory care·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 8, 2026

Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders

Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders

Published on: August 18, 2023

Sleep-disordered breathing and cardiovascular disorders.

Rohit Budhiraja¹, Pooja Budhiraja, Stuart F Quan

¹Division of Sleep Medicine, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02215, USA.

Respiratory Care

|September 30, 2010

Summary

This summary is machine-generated.

Sleep-disordered breathing (SDB) is strongly linked to cardiovascular issues like hypertension and heart disease. Treating SDB, such as with continuous positive airway pressure (CPAP), may improve cardiovascular health and reduce risks.

More Related Videos

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Published on: October 18, 2024

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Related Experiment Videos

Last Updated: Jun 8, 2026

Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders

Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders

Published on: August 18, 2023

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Published on: October 18, 2024

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Area of Science:

Cardiology
Sleep Medicine
Pulmonology

Background:

Sleep-disordered breathing (SDB) encompasses conditions like obstructive sleep apnea (OSA) and central sleep apnea.
SDB is prevalent in patients with cardiovascular disorders, particularly hypertension and heart failure.
Growing evidence suggests a significant association between SDB and various cardiovascular diseases.

Purpose of the Study:

To review the association between SDB and major cardiovascular disorders.
To evaluate the impact of SDB treatment on cardiovascular outcomes.
To identify SDB as a potential risk factor for cardiovascular disease.

Main Methods:

Systematic review of epidemiologic and clinic-based studies.
Analysis of data from randomized controlled trials on SDB treatment.
Evaluation of evidence linking SDB to hypertension, coronary artery disease, heart failure, arrhythmias, and stroke.

Main Results:

A strong association exists between SDB and hypertension, with OSA potentially playing an etiological role.
Continuous positive airway pressure (CPAP) therapy may improve early atherosclerosis and reduce hypertension.
SDB is linked to increased risk of arrhythmias, and CPAP treatment appears to attenuate this risk. Evidence for SDB's role in heart failure and stroke is emerging.

Conclusions:

Compelling evidence supports a probable causal link between SDB and several cardiovascular disorders.
Therapy for SDB, particularly CPAP, shows promise in managing and potentially preventing cardiovascular diseases.
Further large-scale randomized controlled trials are needed to confirm these associations and the benefits of SDB treatment.