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Related Experiment Video

Updated: Jun 8, 2026

Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling

Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling

Published on: October 11, 2018

What is "abnormal" in pediatric sleep?

Leila Kheirandish-Gozal¹

¹Department of Pediatrics and Comer Children's Hospital, Pritzker School of Medicine, University of Chicago, Chicago, IL 60637, USA. lgozal@peds.bsd.uchicago.edu

Respiratory Care

|September 30, 2010

Summary

This summary is machine-generated.

Diagnosing obstructive sleep apnea in children is challenging due to limited access to pediatric sleep studies. Novel biomarker approaches are needed for more reliable pediatric sleep-disordered breathing diagnosis.

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Last Updated: Jun 8, 2026

Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling

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How to Obtain Reliable Visual Event-related Potentials in Newborns

How to Obtain Reliable Visual Event-related Potentials in Newborns

Published on: October 24, 2019

Area of Science:

Pediatric Pulmonology
Sleep Medicine

Background:

Sleep-disordered breathing (SDB) and obstructive sleep apnea (OSA) are common in children.
Current diagnostic methods like polysomnography (PSG) are resource-intensive and inaccessible, leading to underdiagnosis.

Purpose of the Study:

To highlight the diagnostic challenges in pediatric SDB.
To advocate for the development of novel diagnostic approaches using biomarkers and validated algorithms.

Main Methods:

Review of current diagnostic limitations for pediatric sleep apnea.
Discussion of the need for normative data and cost-effectiveness studies for PSG.

Main Results:

Lack of consensus on abnormal PSG criteria hinders diagnosis.
Limited availability of pediatric sleep centers restricts PSG use.

Conclusions:

Validated data and consensus on PSG interpretation are lacking.
Biomarker incorporation into algorithms offers a promising alternative for pragmatic pediatric SDB diagnosis.